Brouwers, Joachim: шукати на сайті Z-Library

Рік:

2017

Мова:

english

Файл:

PDF, 1.18 MB

english, 2017

In vivo methods for drug absorption – Comparative physiologies, model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API/excipient characterization including food effects

Sjögren, Erik, Abrahamsson, Bertil, Augustijns, Patrick, Becker, Dieter, Bolger, Michael B., Brewster, Marcus, Brouwers, Joachim, Flanagan, Talia, Harwood, Matthew, Heinen, Christian, Holm, René, Jure

Журнал:

Berben, Philippe, Bauer-Brandl, Annette, Brandl, Martin, Faller, Bernard, Flaten, Gøril Eide, Jacobsen, Ann-Christin, Brouwers, Joachim, Augustijns, Patrick

Рік:

2014

Мова:

english

Файл:

PDF, 5.20 MB

english, 2014

Drug permeability profiling using cell-free permeation tools: Overview and applications

Журнал:

European Journal of Pharmaceutics and Biopharmaceutics

Рік:

2018

Мова:

english

Файл:

PDF, 1.59 MB

english, 2018

In vitro models for the prediction of in vivo performance of oral dosage forms: recent progress from partnership through the IMI OrBiTo collaboration

Butler, James, Hens, Bart, Vertzoni, Maria, Brouwers, Joachim, Berben, Philippe, Dressman, Jennifer, Andreas, Cord J., Julia Schaefer, Kerstin, Mann, James, McAllister, Mark, Jamei, Masoud, Kostewicz,

Журнал:

Рік:

2018

Мова:

english

Файл:

PDF, 2.35 MB

english, 2018

Drug supersaturation in simulated and human intestinal fluids representing different nutritional states

Jan Bevernage, Joachim Brouwers, Sarah Clarysse, Maria Vertzoni, Jan Tack, Pieter Annaert, Patrick Augustijns

Журнал:

Рік:

2010

Мова:

english

Файл:

PDF, 291 KB

english, 2010

Intestinal drug solubility estimation based on simulated intestinal fluids: Comparison with solubility in human intestinal fluids

Sarah Clarysse, Joachim Brouwers, Jan Tack, Pieter Annaert, Patrick Augustijns

Журнал:

Jeroen Walravens, Joachim Brouwers, Isabel Spriet, Jan Tack, Pieter Annaert, Professor Patrick Augustijns

Рік:

2011

Мова:

english

Файл:

PDF, 605 KB

english, 2011

Effect of pH and Comedication on Gastrointestinal Absorption of Posaconazole

Журнал:

Clinical Pharmacokinetics

Рік:

2011

Мова:

english

Файл:

PDF, 204 KB

english, 2011

In vitro models for the prediction of in vivo performance of oral dosage forms

Kostewicz, Edmund S., Abrahamsson, Bertil, Brewster, Marcus, Brouwers, Joachim, Butler, James, Carlert, Sara, Dickinson, Paul A., Dressman, Jennifer, Holm, René, Klein, Sandra, Mann, James, McAllister

Журнал:

Grammen, Carolien, Van den Mooter, Guy, Appeltans, Bernard, Michiels, Johan, Crucitti, Tania, Ariën, Kevin K., Augustyns, Koen, Augustijns, Patrick, Brouwers, Joachim

Рік:

2014

Мова:

english

Файл:

PDF, 1.41 MB

english, 2014

Development and characterization of a solid dispersion film for the vaginal application of the anti-HIV microbicide UAMC01398

Журнал:

European Journal of Pharmaceutics and Biopharmaceutics

Рік:

2014

Мова:

english

Файл:

PDF, 655 KB

english, 2014

Rapid conversion of the ester prodrug abiraterone acetate results in intestinal supersaturation and enhanced absorption of abiraterone: In vitro, rat in situ and human in vivo studies

Stappaerts, Jef, Geboers, Sophie, Snoeys, Jan, Brouwers, Joachim, Tack, Jan, Annaert, Pieter, Augustijns, Patrick

Журнал:

Рік:

2015

Мова:

english

Файл:

PDF, 418 KB

english, 2015

Characterization of Human Duodenal Fluids in Fasted and Fed State Conditions

Riethorst, Danny, Mols, Raf, Duchateau, Guus, Tack, Jan, Brouwers, Joachim, Augustijns, Patrick

Журнал:

Kourentas, Alexandros, Vertzoni, Maria, Stavrinoudakis, Nick, Symillidis, Alexandros, Brouwers, Joachim, Augustijns, Patrick, Reppas, Christos, Symillides, Mira

Рік:

2015

Мова:

english

Файл:

PDF, 1.24 MB

english, 2015

An in vitro biorelevant gastrointestinal transfer (BioGIT) system for forecasting concentrations in the fasted upper small intestine: Design, implementation, and evaluation

Журнал:

Van Den Abeele, Jens, Rubbens, Jari, Brouwers, Joachim, Augustijns, Patrick

Рік:

2016

Мова:

english

Файл:

PDF, 832 KB

english, 2016

The dynamic gastric environment and its impact on drug and formulation behaviour

Журнал:

Rubbens, Jari, Brouwers, Joachim, Tack, Jan, Augustijns, Patrick

Рік:

2016

Мова:

english

Файл:

PDF, 1.48 MB

english, 2016

Gastrointestinal dissolution, supersaturation and precipitation of the weak base indinavir in healthy volunteers

Журнал:

European Journal of Pharmaceutics and Biopharmaceutics

Рік:

2016

Мова:

english

Файл:

PDF, 1.12 MB

english, 2016

GASTROINTESTINAL AND SYSTEMIC DISPOSITION OF DICLOFENAC UNDER FASTED AND FED STATE CONDITIONS SUPPORTING THE EVALUATION OF IN VITRO PREDICTIVE TOOLS

Van Den Abeele, Jens, Schilderink, Ronald, Schneider, FElix, Mols, Raf, Minekus, Mans, Weitschies, Werner, Brouwers, Joachim, Tack, Jan, Augustijns, Patrick

Журнал:

Boyd, Ben J., Bergström, Christel A.S., Vinarov, Zahari, Kuentz, Martin, Brouwers, Joachim, Augustijns, Patrick, Brandl, Martin, Bernkop-Schnürch, Andreas, Shrestha, Neha, Préat, Véronique, Müllertz,

Рік:

2017

Мова:

english

Файл:

PDF, 1.82 MB

english, 2017

Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems

Журнал:

Braeckmans, Marlies, Brouwers, Joachim, Masuy, Imke, Servais, Cécile, Tack, Jan, Augustijns, Patrick

Рік:

2019

Мова:

english

Файл:

PDF, 1.58 MB

english, 2019

The influence of gastric motility on the intraluminal behavior of fosamprenavir

Журнал:

van Leeuwen, Fijs W.B., Schottelius, Margret, Brouwer, Oscar Roberto, Vidal-Sicart, Sergi, Achilefu, Samuel, Klode, Joachim, Wester, Hans-Jurgen, Buckle, Tessa

Рік:

2019

Мова:

english

Файл:

PDF, 1.39 MB

english, 2019

Trending: Radioactive and fluorescent bimodal/hybrid tracers as multiplexing solutions for surgical guidance

Журнал:

Journal of Nuclear Medicine

Рік:

2019

Мова:

english

Файл:

PDF, 1.61 MB

english, 2019

Trending: Radioactive and fluorescent bimodal/hybrid tracers as multiplexing solutions for surgical guidance

van Leeuwen, Fijs W.B., Schottelius, Margret, Brouwer, Oscar Roberto, Vidal-Sicart, Sergi, Achilefu, Samuel, Klode, Joachim, Wester, Hans-Jurgen, Buckle, Tessa

Журнал:

Journal of Nuclear Medicine

Рік:

2019

Файл:

PDF, 1.61 MB

2019

Multidimensional analysis of human intestinal fluid composition

Pyper, Kate, Brouwers, Joachim, Augustijns, Patrick, Khadra, I., Dunn, C., Wilson, C.G., Halbert, G.W.

Журнал:

European Journal of Pharmaceutics and Biopharmaceutics

Рік:

2020

Файл:

PDF, 1.66 MB

2020

Validation of a differential in situ perfusion method with mesenteric blood sampling in rats for intestinal drug interaction profiling

Joachim Brouwers, Raf Mols, Pieter Annaert, Patrick Augustijns

Журнал:

Biopharmaceutics & Drug Disposition

Рік:

2010

Мова:

english

Файл:

PDF, 201 KB

english, 2010

Intraluminal drug and formulation behavior and integration in in vitro permeability estimation: A case study with amprenavir

Joachim Brouwers, Jan Tack, Frank Lammert, Patrick Augustijns

Журнал:

Joachim Brouwers, Marcus E. Brewster, Patrick Augustijns

Рік:

2006

Мова:

english

Файл:

PDF, 199 KB

english, 2006

Supersaturating drug delivery systems: The answer to solubility-limited oral bioavailability?

Журнал:

Joachim Brouwers, Jan Tack, Patrick Augustijns

Рік:

2009

Мова:

english

Файл:

PDF, 648 KB

english, 2009

In vitro behavior of a phosphate ester prodrug of amprenavir in human intestinal fluids and in the Caco-2 system: Illustration of intraluminal supersaturation

Журнал:

Joachim Brouwers, Jan Tack, Patrick Augustijns

Рік:

2007

Мова:

english

Файл:

PDF, 464 KB

english, 2007

Parallel Monitoring of Plasma and Intraluminal Drug Concentrations in Man After Oral Administration of Fosamprenavir in the Fasted and Fed State

Журнал:

Pharmaceutical Research

Рік:

2007

Мова:

english

Файл:

PDF, 276 KB

english, 2007

Postprandial Changes in Solubilizing Capacity of Human Intestinal Fluids for BCS Class II Drugs

Sarah Clarysse, Dimitrios Psachoulias, Joachim Brouwers, Jan Tack, Pieter Annaert, Guus Duchateau, Christos Reppas, Patrick Augustijns

Журнал:

Pharmaceutical Research

Рік:

2009

Мова:

english

Файл:

PDF, 248 KB

english, 2009

Capillary zone electrophoresis method development for the analysis of Hippeastrum hybrid agglutinin samples

Alexandre Zatkovskis Carvalho, Tine Dupas, Joachim Brouwers, Jos Hoogmartens, Patrick Augustijns, Ann Van Schepdael

Журнал:

Journal of Chromatography B

Рік:

2009

Мова:

english

Файл:

PDF, 389 KB

english, 2009

Determination of intraluminal theophylline concentrations after oral intake of an immediate-and a slow-release dosage form

Joachim Brouwers, Françoise Ingels, Jan Tack, Patrick Augustijns

Журнал:

Journal of Pharmacy and Pharmacology

Рік:

2005

Мова:

english

Файл:

PDF, 176 KB

english, 2005

CADA, a Potential Anti-HIV Microbicide that Specifically Targets the Cellular CD4 Receptor

Kurt Vermeire, Thomas Bell, Roger Le Grand, Joachim Brouwers, Patrick Augustijns, Dominique Schols

Журнал:

Kurt Vermeire, Joachim Brouwers, Patrick Augustijns, Dominique Schols

Рік:

2009

Мова:

english

Файл:

PDF, 111 KB

english, 2009

Development and In Vitro Evaluation of Gel-formulated Saquinavir as Vaginal Microbicide: Anti-HIV-1 Activity and Pharmaceutical Availability in Biorelevant Media

Журнал:

Joachim Brouwers, Kurt Vermeire, Carolien Grammen, Dominique Schols, Patrick Augustijns

Рік:

2010

Мова:

english

Файл:

PDF, 82 KB

english, 2010

Early identification of availability issues for poorly water-soluble microbicide candidates in biorelevant media: A case study with saquinavir

Журнал:

Рік:

2011

Мова:

english

Файл:

PDF, 408 KB

english, 2011

Ex vivo permeability experiments in excised rat intestinal tissue and in vitro solubility measurements in aspirated human intestinal fluids support age-dependent oral drug absorption

Pieter Annaert, Joachim Brouwers, Ann Bijnens, Frank Lammert, Jan Tack, Patrick Augustijns

Журнал:

Joachim Brouwers, Kurt Vermeire, Dominique Schols, Patrick Augustijns

Рік:

2010

Мова:

english

Файл:

PDF, 477 KB

english, 2010

Development and in vitro evaluation of chloroquine gels as microbicides against HIV-1 infection

Журнал:

Virology

Рік:

2008

Мова:

english

Файл:

PDF, 173 KB

english, 2008

Food-dependent disintegration of immediate release fosamprenavir tablets: In vitro evaluation using magnetic resonance imaging and a dynamic gastrointestinal system

Joachim Brouwers, Bart Anneveld, Gert-Jan Goudappel, Guus Duchateau, Pieter Annaert, Patrick Augustijns, Evelijn Zeijdner

Журнал:

European Journal of Pharmaceutics and Biopharmaceutics

Рік:

2011

Мова:

english

Файл:

PDF, 621 KB

english, 2011

Supersaturation in human gastric fluids

Jan Bevernage, Bart Hens, Joachim Brouwers, Jan Tack, Pieter Annaert, Patrick Augustijns

Журнал:

European Journal of Pharmaceutics and Biopharmaceutics

Рік:

2012

Мова:

english

Файл:

PDF, 483 KB

english, 2012

Excipient-Mediated Supersaturation Stabilization in Human Intestinal Fluids

Bevernage, Jan, Forier, Thomas, Brouwers, Joachim, Tack, Jan, Annaert, Pieter, Augustijns, Patrick

Журнал:

Carolien Grammen, Patrick Augustijns, Joachim Brouwers

Рік:

2011

Мова:

english

Файл:

PDF, 2.13 MB

english, 2011

In vitro profiling of the vaginal permeation potential of anti-HIV microbicides and the influence of formulation excipients

Журнал:

Jan Bevernage, Joachim Brouwers, Pieter Annaert, Patrick Augustijns

Рік:

2012

Мова:

english

Файл:

PDF, 630 KB

english, 2012

Drug precipitation–permeation interplay: Supersaturation in an absorptive environment

Журнал:

European Journal of Pharmaceutics and Biopharmaceutics

Рік:

2012

Мова:

english

Файл:

PDF, 222 KB

english, 2012

Evaluation of gastrointestinal drug supersaturation and precipitation: Strategies and issues

Bevernage, Jan, Brouwers, Joachim, Brewster, Marcus E., Augustijns, Patrick

Журнал:

Рік:

2013

Мова:

english

Файл:

PDF, 1.48 MB

english, 2013

Solubility Profiling of HIV Protease Inhibitors in Human Intestinal Fluids

Wuyts, Benjamin, Brouwers, Joachim, Mols, Raf, Tack, Jan, Annaert, Pieter, Augustijns, Patrick

Журнал:

Gorlani, Andrea, Brouwers, Joachim, McConville, Christopher, van der Bijl, Pieter, Malcolm, Karl, Augustijns, Patrick, Quigley, Anna Forsman, Weiss, Robin, De Haard, Hans, Verrips, Theo

Рік:

2013

Мова:

english

Файл:

PDF, 973 KB

english, 2013

Llama Antibody Fragments Have Good Potential for Application as HIV Type 1 Topical Microbicides

Журнал:

AIDS Research and Human Retroviruses

Рік:

2012

Мова:

english

Файл:

PDF, 290 KB

english, 2012

Association of 25-Hydroxyvitamin D and Parathyroid Hormone With Incident Hypertension

van Ballegooijen, Adriana J., Kestenbaum, Bryan, Sachs, Michael C., de Boer, Ian H., Siscovick, David S., Hoofnagle, Andrew N., Ix, Joachim H., Visser, Marjolein, Brouwer, Ingeborg A.

Журнал:

Journal of the American College of Cardiology

Рік:

2014

Мова:

english

Файл:

PDF, 516 KB

english, 2014

A review of drug solubility in human intestinal fluids: Implications for the prediction of oral absorption

Augustijns, Patrick, Wuyts, Benjamin, Hens, Bart, Annaert, Pieter, Butler, James, Brouwers, Joachim

Журнал:

Zhu, Mingyao, Bzdusek, Karl, Brink, Carsten, Eriksen, Jesper Grau, Hansen, Olfred, Jensen, Helle Anita, Gay, Hiram A., Thorstad, Wade, Widder, Joachim, Brouwer, Charlotte L., Steenbakkers, Roel J.H.M.

Рік:

2014

Мова:

english

Файл:

PDF, 556 KB

english, 2014

Multi-institutional Quantitative Evaluation and Clinical Validation of Smart Probabilistic Image Contouring Engine (SPICE) Autosegmentation of Target Structures and Normal Tissues on Computer Tomography Images in the Head and Neck, Thorax, Liver, and Male Pelvis Areas

Журнал:

International Journal of Radiation Oncology*Biology*Physics

Рік:

2013

Мова:

english

Файл:

PDF, 2.14 MB

english, 2013

Resolving intraluminal drug and formulation behavior: Gastrointestinal concentration profiling in humans

Brouwers, Joachim, Augustijns, Patrick

Журнал:

Рік:

2014

Мова:

english

Файл:

PDF, 1.54 MB

english, 2014

Gastrointestinal transfer: In vivo evaluation and implementation in in vitro and in silico predictive tools

Hens, Bart, Brouwers, Joachim, Anneveld, Bart, Corsetti, Maura, Symillides, Mira, Vertzoni, Maria, Reppas, Christos, Turner, David B., Augustijns, Patrick

Журнал:

Рік:

2014

Мова:

english

Файл:

PDF, 1.04 MB

english, 2014

Vaginal Expression of Efflux Transporters and the Potential Impact on the Disposition of Microbicides in Vitro and in Rabbits

Grammen, Carolien, Baes, Myriam, Haenen, Steven, Verguts, Jasper, Augustyns, Koen, Zydowsky, Thomas, La Colla, Paolo, Augustijns, Patrick, Brouwers, Joachim

Журнал:

Stappaerts, Jef, Brouwers, Joachim, Annaert, Pieter, Augustijns, Patrick

Рік:

2014

Мова:

english

Файл:

PDF, 1.45 MB

english, 2014

In situ perfusion in rodents to explore intestinal drug absorption: Challenges and opportunities

Журнал:

Wuyts, Benjamin, Riethorst, Danny, Brouwers, Joachim, Tack, Jan, Annaert, Pieter, Augustijns, Patrick

Рік:

2015

Мова:

english

Файл:

PDF, 1.44 MB

english, 2015

Evaluation of fasted state human intestinal fluid as apical solvent system in the Caco-2 absorption model and comparison with FaSSIF

Журнал: